Article

A systems genomics approach uncovers molecular associates of RSV severity

2020-12-19

Abstract excerpt

Globally, RSV infection results in millions of hospitalizations and thousands of deaths each year. Specific factors that contribute to disease severity, such as premature birth and certain comorbidities, are well established. Additionally, genetic variants resulting in alterations in the adaptive and innate immune response appear to be associated with RSV severity. While previous studies focused on a single aspect...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 8d997563-3bf6-5f31-8dc0-2cb9ca219f63
DOI: 10.1101/2020.12.18.423266

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A systems genomics approach uncovers molecular associates of RSV severityDOI 10.1101/2020.12.18.423266Read

Integrated omics endotyping of infants with respiratory syncytial virus bronchiolitis and risk of childhood asthma.Semantic proximity Read

Association of Dynamic Changes in the CD4 T-Cell Transcriptome With Disease Severity During Primary Respiratory Syncytial Virus Infection in Young InfantsSemantic proximity Read

Comprehensive analysis of the nasopharyngeal microbiome and host transcriptome in children with varying severity of respiratory syncytial virus infectionSemantic proximity Read

Microbiome-Transcriptome Interactions Related to Severity of Respiratory Syncytial Virus InfectionSemantic proximity Read

Airway Gene Expression Correlates of Respiratory Syncytial Virus Disease Severity and Microbiome Composition in InfantsSemantic proximity Read

Multi-omics to study chronic respiratory diseases and viral infections.Semantic proximity Read

Airway Gene-Expression Classifiers for Respiratory Syncytial Virus (RSV) Disease Severity in InfantsSemantic proximity Read

Olfactomedin 4 Serves as a Marker for Disease Severity in Pediatric Respiratory Syncytial Virus (RSV) InfectionSemantic proximity Read

Advancing our understanding of infant bronchiolitis through phenotyping and endotyping: clinical and molecular approaches.Semantic proximity Read

Whole Blood Gene Expression Profiles to Assess Pathogenesis and Disease Severity in Infants with Respiratory Syncytial Virus InfectionSemantic proximity Read

Nasopharyngeal Microbiota, Host Transcriptome, and Disease Severity in Children with Respiratory Syncytial Virus InfectionSemantic proximity Read

Factors Affecting the Immunity to Respiratory Syncytial Virus: From Epigenetics to Microbiome.Semantic proximity Read