Article

Patient-specific gene networks reveal novel subtypes and predictive biomarkers in lung cancer

2024-08-08

Abstract excerpt

Lung adenocarcinoma (LUAD) is an aggressive form of non-small cell lung cancer. Genome-wide gene co-expression networks (GCNs) has been paramount to describe changes in the transcriptional regulatory programs found between diseased and healthy states of LUAD. Multiple cancerous phenotypes share a distinct GCN architecture, suggesting that network topology holds promise for understanding disease pathology. However,...

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Literature Corpus work: 8d862a43-d6aa-5964-a33a-154829e2ccc8
DOI: 10.1101/2024.08.06.606802

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