Article

Harnessing Global HLA Data for Enhanced Patient Matching in iPSC Haplobanks

2024-10-17

Abstract excerpt

Several countries have either developed or are developing national induced pluripotent stem cell (iPSC) banks of cell lines derived from donors with HLA homozygous genotypes (two identical haplotypes) prevalent in their local populations to provide immune matched tissues and cells to support regenerative medicine therapies. This ‘haplobank’ approach relies on knowledge of the HLA genotypes of the population to ide...

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Literature Corpus work: 8d532f30-6349-566c-b2d8-4d084893b5f5
DOI: 10.1101/2024.10.15.618361

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