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Isotretinoin treatment upregulates the expression of p53 in the skin and sebaceous glands of patients with acne vulgaris

2022-12-13

Abstract excerpt

The transcriptomic regulation induced by isotretinoin ( 13-cis retinoic acid) is still a matter of debate as short-term exposures of immortalized sebocytes with isotretinoin produced conflicting results. Based on translational evidence, it has been hypothesized that oral isotretinoin treatment upregulates the expression of the transcription factor p53. Twenty-five patients suffering from acne vulgaris were treated...

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Literature Corpus work
8ca3709c-799c-5a33-b7fe-9a2fdc897111
DOI
10.21203/rs.3.rs-1609874/v2
Open publication

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