Article

Goal-directed action is transiently impaired in an hAPP-J20 mouse model of Alzheimer’s disease, and in aging male mice regardless of genotype

2022-07-25

Abstract excerpt

Cognitive-behavioural testing in preclinical models of Alzheimer’s disease has typically been limited to visuo-spatial memory tests and has failed to capture the broad scope of deficits patients also display in goal-directed action control. The current study addresses this gap by providing the first comprehensive investigation of how goal-directed actions are affected in a transgenic mouse model of Alzheimer’s dis...

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Literature Corpus work: 8c9a50e3-a893-59e6-a43a-8888b436393c
DOI: 10.1101/2022.07.25.501480

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Goal-directed action is transiently impaired in an hAPP-J20 mouse model of Alzheimer’s disease, and in aging male mice regardless of genotypeDOI 10.1101/2022.07.25.501480Read

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