Article

Reclassification of Genetic Variants in Patients with Hypertrophic Cardiomyopathy from the Sarcomeric Human Cardiomyopathy Registry (SHaRe)

2026-08-10

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Genetic testing is a Class I recommendation for patients with hypertrophic cardiomyopathy (HCM). As knowledge and frameworks continue to evolve, genetic variant classifications may change with new evidence over time. Classifications rely on evidence sought from publicly available case data, improved classification rules, and gene-disease validity. We evaluated the frequency...

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Literature Corpus work: 8c70d1d9-0898-51dc-9a9b-9a2222773fb2
DOI: 10.64898/2026.08.05.26359735

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