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SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylation

2022-03-15

Abstract excerpt

<title>Abstract</title> <p>Increasing research has uncovered the involvement of long non-coding RNAs (lncRNAs) in the progression of multiple cancers including lung adenocarcinoma (LUAD). RT-qPCR and western blot were done to measure RNAs and proteins. Functional assays assessed LUAD cell biological behaviors under knockdown or overexpression of LINC01468, SIX5, SERBP1 or SERPINE1, and the specific function of th...

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Literature Corpus work
8bb2ff12-299d-5183-9522-3a2ea5aa9a2e
DOI
10.21203/rs.3.rs-712175/v1
Open publication

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SIX5-activated LINC01468 promotes lung adenocarcinoma progression by recruiting SERBP1 to regulate SERPINE1 mRNA stability and recruiting USP5 to facilitate PAI1 protein deubiquitylationDOI 10.21203/rs.3.rs-712175/v1
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