JNK signaling regulates reproductive trade-offs after <i>Plasmodium</i> infection in the malaria mosquito

Abstract excerpt

<h4>ABSTRACT</h4> Environmental stress can limit mammalian reproduction by affecting production of sexual steroid hormones. Here we reveal a similar mechanism in the malarial mosquito Anopheles gambiae : activation of the stress-sensitive c- J un N -terminal k inase, JNK, constrains reproductive investment by suppressing production of ecdysteroids that orchestrate egg development in this species. We show that...

Topics

Open a Topic to create a Post that cites this publication.

• Complement system in diseases
• Insect symbiosis and bacterial influences
• Invertebrate Immune Response Mechanisms
• Malaria Research and Control
• Mosquito-borne diseases and control
• Neurobiology and Insect Physiology Research

Identifiers and source

Literature Corpus work

8b429725-6174-5e25-b33a-084c598ea7de

DOI

10.1101/2025.09.03.673998