Article

Comparative Transcriptomes of Canine and Human Prostate Cancers Identify Mediators of Castration Resistance

2024-08-18

Abstract excerpt

Prostate cancer continues to be one of the most lethal cancers in men. While androgen-deprivation therapy is initially effective in treating prostate cancer, most cases of advanced prostate cancer eventually progress to castration-resistant prostate cancer (CRPC), which is incurable. Similarly, the most aggressive form of prostatic carcinoma occurs in dogs that have been castrated. To identify molecular similariti...

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Literature Corpus work: 8b136245-c24c-5fe9-83a0-573cb804cbf9
DOI: 10.1101/2024.08.18.608482

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