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Machine learning–derived exosome-related biomarkers for prostate cancer diagnosis and AKR1B1-centered functional characterization

2026-07-22

Abstract excerpt

<title>Abstract</title> <p>Exosomes play critical roles in prostate cancer (PRAD) progression. This study aimed to identify and validate exosome-related diagnostic biomarkers for PRAD using integrated bioinformatics and machine learning approaches. Transcriptomic data from TCGA-PRAD and three GEO cohorts were intersected with curated exosome-related gene sets to obtain exosome-related DEGs (Exo-DEGs). Core diagno...

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Literature Corpus work
8b007f1b-cbb7-5c6f-b133-d960eaba7da0
DOI
10.21203/rs.3.rs-9681475/v1
Open publication

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Machine learning–derived exosome-related biomarkers for prostate cancer diagnosis and AKR1B1-centered functional characterizationDOI 10.21203/rs.3.rs-9681475/v1
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