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Article

Evolving patterns of antimalarial drug resistance markers in symptomatic infections in Kenya, 2013-2022.

Parasites & vectors - 6 Feb 2026

Magudha John, Ndwiga Leonard, Akinyi Mercy Y, Wamae Kevin, Osoti Victor, Kandie Regina, Kiplagat Rosebella, Keitany Kibor, Bargul Joel L, Akala Hoseah M, Ochola-Oyier L Isabella

Abstract excerpt

BACKGROUND: Ongoing antimalarial drug resistance surveillance is essential to guide effective treatment strategies. Historically, resistance to chloroquine and sulfadoxine-pyrimethamine (SP) has been associated with well-characterized mutations in the chloroquine resistance transporter (Pfcrt; K76T) and antifolate pathway genes, including dihydrofolate reductase (Pfdhfr; N51I, C59R, S108N) and dihydropteroate...

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Identifiers

PMID: 41652479
DOI: 10.1186/s13071-026-07280-w
PMCID: PMC12973677

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