Article
Childhood Cancer Predisposition: An Overview for the General Pediatrician.
Pediatric annals - 1 Jan 2022
Kagami Laura, Baldino Sarah, MacFarland Suzanne P
Abstract excerpt
Cancer predisposition syndromes (CPS), or genetic syndromes leading to increased cancer risk, are responsible for at least 10% of all childhood cancers. With advances in both tumor and germline sequencing, these syndromes have been uncovered both in patients with and without syndromic features and family history of cancer. Recognition of CPS in children and use of associated screening guidelines can improve...
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