Article
A phase I window-of-opportunity study of neoadjuvant avelumab and hypofractionated radiation therapy in radiation-relapsed meningioma
2025-09-28
Abstract excerpt
Effective treatments for recurrent, radiation-relapsed meningiomas (RR-meningiomas) following surgery and radiation therapy (RT) are limited. Inhibitors of the programmed-death-1 (PD-1) or programmed-death ligand-1 (PD-L1) pathway have shown modest activity in single-arm phase II studies of RR-meningiomas. This study aimed to evaluate the immunological effects of combining avelumab, a PD-L1 inhibitory antibody, wi...
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Identifiers and source
- Literature Corpus work
- 896a8a3a-5a74-5cd8-ab29-ba760f81353c
- DOI
- 10.1101/2025.09.26.25336740