Article

Molecular Impact of Metabolic and Endocrine Disturbance on Endometrial Function in Polycystic Ovary Syndrome

2025-09-15

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a systemic metabolic and endocrine disorder that significantly disrupts reproductive physiology and endometrial function. In this narrative review, we examine the molecular impact of metabolic and hormonal imbalances on the endometrium of women with PCOS. We investigate the specific mechanisms that delineate how hyperinsulinemia and insulin resistance, chronic low-grade inflamma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 89565509-449b-5b95-9af1-9f82ccde1bbc
DOI: 10.20944/preprints202509.1235.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Molecular Impact of Metabolic and Endocrine Disturbance on Endometrial Function in Polycystic Ovary SyndromeDOI 10.20944/preprints202509.1235.v1Read

Scientific Statement on the Diagnostic Criteria, Epidemiology, Pathophysiology, and Molecular Genetics of Polycystic Ovary SyndromeSemantic proximity Read

Updates in diagnosing polycystic ovary syndrome-related infertility.Semantic proximity Read

Modulation of the Inflammatory Response in Polycystic Ovary Syndrome (PCOS)—Searching for Epigenetic FactorsSemantic proximity Read

Pathomechanisms of polycystic ovary syndrome Multidimensional approachesSemantic proximity Read

Inflammation and reproductive function in women with polycystic ovary syndromeSemantic proximity Read

A Systems-Level Transcriptomic Analysis of Polycystic Ovary Syndrome as a Mitochondrial-Immunometabolic DisorderSemantic proximity Read

Proteomic and bioinformatic analysis of human endometrium from polycystic ovarian syndrome with and without insulin resistanceSemantic proximity Read

POLYCYSTIC OVARY SYNDROME: ORIGINS AND IMPLICATIONS: Epidemiological aspects of polycystic ovary syndrome.Semantic proximity Read

Pathogenetic analysis of polycystic ovary syndrome from the perspective of omicsSemantic proximity Read

Hyperandrogenic Milieu Dysregulates the Expression of Insulin Signaling Factors and Glucose Transporters in the Endometrium of Patients With Polycystic Ovary SyndromeSemantic proximity Read

Genomic and proteomic evidence for hormonal and metabolic foundations of polycystic ovary syndromeSemantic proximity Read

The Ovary–Liver Axis: Molecular Science and EpidemiologySemantic proximity Read