Metabolic network construction reveals probiotic-specific alterations in the metabolic activity of a synthetic small intestinal community

Abstract excerpt

The gut microbiota plays a crucial role in maintaining overall health and probiotics have emerged as a promising microbiota-targeted therapy for improving human health. However, the molecular mechanisms of probiotics action in general and the targeting of small intestinal microbiota by probiotics are not well understood. To address this, we constructed a synthetic community of three species, which resembles the up...

Topics

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• 3D Printing in Biomedical Research
• Clostridium difficile and Clostridium perfringens research
• Diet and metabolism studies
• Gut microbiota and health
• Microbial Metabolic Engineering and Bioproduction
• Pancreatic function and diabetes
• Probiotics and Fermented Foods

Identifiers and source

Literature Corpus work

8940bbec-c459-5da5-97dc-f066d1d206a4

DOI

10.1101/2023.03.29.534679