Back to search

Article

Insertion sequence elements associated with <i>Staphylococcus epidermidis</i> evolution in persistent orthopaedic device-related infections

2026-05-24

Abstract excerpt

<h4>Background</h4> Staphylococcus epidermidis is a major cause of orthopaedic device-related infections (ODRIs), which are often challenging to treat due to their extensive antimicrobial resistance (AMR) and biofilm formation. It has been hypothesised that S. epidermidis may rapidly adapt to the medical device niche, enhancing persistence, but direct evidence of within-host pathoadaptive evolution remains limit...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
893ba908-67e1-5e62-8c17-ee395d95cc0d
DOI
10.64898/2026.05.21.726754
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Insertion sequence elements associated with <i>Staphylococcus epidermidis</i> evolution in persistent orthopaedic device-related infectionsDOI 10.64898/2026.05.21.726754
Distinct clonal lineages and within-host diversification shape invasive Staphylococcus epidermidis populations.Semantic proximity
Multiple hypervirulent methicillin-sensitive<i>Staphylococcus aureus</i>lineages contribute towards poor patient outcomes in orthopedic device-related infectionsSemantic proximity
Genomic Exploration of Within-Host Microevolution Reveals a Distinctive Molecular Signature of Persistent <i>Staphylococcus aureus</i> BacteraemiaSemantic proximity
Evolution of mobile genetic element composition in an epidemic methicillin-resistant Staphylococcus aureus: temporal changes correlated with frequent loss and gain eventsSemantic proximity
Comparative genomic analysis of resistance and virulence genes in staphylococcus epidermidis and their impact on clinical outcome of musculoskeletal infectionsSemantic proximity
Evolution of Staphylococcus aureus during human colonization and infection.Semantic proximity
Success through diversity - how Staphylococcus epidermidis establishes as a nosocomial pathogen.Semantic proximity
Impact of Insertion Sequences and Recombination on the Population Structure of Staphylococcus haemolyticus.Semantic proximity
Nosocomial infections by Staphylococcus epidermidis: how a commensal bacterium turns into a pathogen.Semantic proximity
Massive genome decay and insertion sequence expansion drive the evolution of a novel host-restricted bacterial pathogenSemantic proximity
Insights on Evolution of Virulence and Resistance from the Complete Genome Analysis of an Early Methicillin-Resistant <i>Staphylococcus aureus</i> Strain and a Biofilm-Producing Methicillin-Resistant <i>Staphylococcus epidermidis</i> StrainSemantic proximity
Key role of quorum‐sensing mutations in the development of Staphylococcus aureus clinical device‐associated infectionSemantic proximity
Select a neighboring publication to make it the new centre.