Article

Integrating GIS and Genomics for AMR One Health Drug Target Discovery in Imipenem-Resistant Escherichia coli

2026-01-23

Abstract excerpt

Background Antimicrobial Resistance (AMR) is a major global health challenge, particularly in Africa, where antibiotic misuse worsens resistance. This study aims to identify potential drug targets in imipenem-resistant E. coli isolates from the Vet-LIRN database through a four-phase approach integrating interactive GIS analysis, genomic data analysis, subtractive genomics, and druggability assessments. Methods Ph...

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Literature Corpus work: 88a9812c-ec61-5fd7-93e5-d70328504feb
DOI: 10.12688/wellcomeopenres.23819.2

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