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WcaJ, the initiating enzyme for colanic acid synthesis, is required for lipopolysaccharide production, biofilm formation and virulence in Edwardsiella tarda

2015-02-01

Abstract excerpt

Edwardsiella tarda, a Gram-negative bacterium, is the causative agent of edwardsiellosis, which is a major problem for the aquaculture industry worldwide. Undecaprenyl-phosphate glycosyltransferase, WcaJ, as the initiating enzyme for colanic acid synthesis, is hypothesized to be involved in the pathogenesis of infection. In this study, a wcaJ in-frame deletion mutant (ΔwcaJ) of a virulent isolate of E. tarda EIB20...

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Literature Corpus work: 88767589-8807-51d8-a76c-c2758a60a67c
DOI: 10.1016/j.aquaculture.2014.12.011

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