Article

Clinical Manifestations and Immunologic Features of Chediak–Higashi Syndrome: A 12-Year National Registry Study from Iran

2026-07-25

Abstract excerpt

<title>Abstract</title> <p> Introduction Chediak–Higashi syndrome (CHS) is a rare autosomal recessive inborn error of immunity caused by biallelic mutations in the <italic>LYST</italic> gene. Population-based data on its clinical and immunological features remain scarce, particularly from Middle Eastern populations. We aimed to characterize the clinical manifestations, immunological findings, and outcomes of...

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Literature Corpus work: 87bf6905-22de-593c-84e0-b0cd0fc6af7a
DOI: 10.21203/rs.3.rs-10383500/v1

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