Article

Genome Mining Reveals the Structure of the Clostrisin and Cellulosin Biosynthetic Gene Clusters, Two Novel Lantibiotics

2023-12-06

Abstract excerpt

Antimicrobial resistance is an issue of enormous proportions that poses a significant threat to global public health. This study focuses on lanthipeptides, ribosomally encoded peptides which display significant structural diversity and hold promising potential as antibiotics. Genome mining was employed to locate biosynthetic gene clusters (BGC) for class II lanthipeptides. A phylogenetic study analyzing homologous...

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Literature Corpus work: 8725cbba-f809-5a2a-a395-24d35498d598
DOI: 10.3762/bxiv.2023.56.v1

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