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Targeted and random mutagenesis of cassava brown streak disease susceptibility factors reveal molecular determinants of disease severity

2025-03-01

Abstract excerpt

Cassava brown streak disease (CBSD) is caused by cassava brown streak viruses (CBSVs) from the family Potyviridae . Potyvirid viral genome-linked protein (VPg) recruitment of host eukaryotic translation initiation factor 4E (eIF4E) proteins is a critical step in the viral life cycle. CBSV VPg interacts with all five cassava eIF4E-family members. Simultaneously knocking out eIF4E- family genes nCBP-1 and nCBP-2...

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Identifiers and source

Literature Corpus work
86f5ee70-4fc0-5052-9ef3-b47a35e10feb
DOI
10.1101/2025.02.27.640518
Open publication

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Targeted and random mutagenesis of cassava brown streak disease susceptibility factors reveal molecular determinants of disease severityDOI 10.1101/2025.02.27.640518
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