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Broadening Virus Resistance Through Gene Pyramiding of eIF4E Family Members.

Molecular plant pathology - 1 Dec 2025

Suzuki Masato, Nishikawa Masanobu, Yamamoto Toya, Koinuma Hiroaki, Keima Takuya, Fujimoto Yuji, Komatsu Ken, Hashimoto Masayoshi, Neriya Yutaro, Maejima Kensaku, Namba Shigetou, Yamaji Yasuyuki

Abstract excerpt

Recessive resistance, achieved through mutations in host susceptibility genes, offers an effective way for controlling plant viruses. One well-studied gene family involved in such resistance is the eukaryotic translation initiation factor 4E (eIF4E) gene family, which includes eIF4E, eIFiso4E and the atypical novel cap-binding protein (nCBP). Although gene pyramiding of the eIF4E family may provide a promising...

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Arabidopsis
Disease Resistance
Eukaryotic Initiation Factor-4E
Gene Knockout Techniques
Multigene Family

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PMID: 41366833
DOI: 10.1111/mpp.70187
PMCID: PMC12689272

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