Article
Classification Models using Circulating Neutrophil Transcripts Can Detect Unruptured Intracranial Aneurysm
2020-09-17
Abstract excerpt
<title>Abstract</title> <p><bold>Background</bold>: Intracranial aneurysms (IAs) are dangerous because of their potential to rupture. We previously found significant RNA expression differences in circulating neutrophils between patients with and without unruptured IAs and trained machine learning models to predict presence of IA using 40 neutrophil transcriptomes. Here, we aim to develop a predictive model for un...
Topics
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- Intracerebral and Subarachnoid Hemorrhage Research
- Intracranial Aneurysms: Treatment and Complications
- Mitochondrial Function and Pathology
- Neuroinflammation and Neurodegeneration Mechanisms
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- S100 Proteins and Annexins
- Traumatic Brain Injury and Neurovascular Disturbances
- Vascular Malformations Diagnosis and Treatment
Identifiers and source
- Literature Corpus work
- 84ef15f1-f0ca-5d3f-a651-add47144d774
- DOI
- 10.21203/rs.3.rs-17161/v2
