Article

Nusinersen rescues taurine deficiency in severe Spinal Muscular Atrophy

2025-07-23

Abstract excerpt

<title>Abstract</title> <p> <bold>Background</bold> Spinal muscular atrophy (SMA), a leading genetic cause of infant mortality resulting from ubiquitous SMN deficiency, disrupts key biological processes such as neurotransmission, oxidative stress, and inflammation, all of which may be modulated by the neurotransmitter taurine. However, it remains uncertain whether a connection exists between SMN deficiency and...

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Literature Corpus work: 84ede6cc-1411-51a8-9840-acfb7be7b1a9
DOI: 10.21203/rs.3.rs-6566128/v1

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