Article

Positive and biphasic extracellular waveforms correspond to return currents and axonal spikes

2023-03-25

Abstract excerpt

Multiple biophysical mechanisms may generate non-negative extracellular waveforms during action potentials, but the origin and prevalence of positive spikes and biphasic spikes in the intact brain are unknown. Using extracellular recordings from densely-connected cortical networks in freely-moving mice, we find that a tenth of the waveforms are non-negative. Positive phases of non-negative spikes occur in synchron...

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Identifiers and source

Literature Corpus work: 8455b962-fb6c-5f67-bfc5-ec3991f35d57
DOI: 10.1101/2023.03.24.534099

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