Article

Gas Vesicle-Expressing Human Pluripotent Stem Cells Enable Multimodal Ultrasound and Optical Coherence Tomographic Imaging

2025-04-10

Abstract excerpt

<h4>Summary</h4> Genetically encoded imaging reporters are critical tools for tracking cell fate and function in regenerative medicine. Gas vesicles (GVs), air-filled protein nanostructures derived from bacteria, offer unique advantages for noninvasive imaging due to their acoustic and optical properties. In this study, we engineered human pluripotent stem cells (hPSCs) to express GVs using a doxycycline-inducibl...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 840fd317-fadd-5b23-85b4-9ff5ea437f2f
DOI: 10.1101/2025.04.10.648235

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gas Vesicle-Expressing Human Pluripotent Stem Cells Enable Multimodal Ultrasound and Optical Coherence Tomographic ImagingDOI 10.1101/2025.04.10.648235Read

Acoustically Detonated Biomolecules for Genetically Encodable Inertial CavitationSemantic proximity Read

Non-invasive imaging of cell-based therapies using acoustic reporter genesSemantic proximity Read

Gas vesicle-blood interactions enhance ultrasound imaging contrastSemantic proximity Read

50-nm gas-filled protein nanostructures to enable the access of lymphatic cells by ultrasound technologiesSemantic proximity Read

Ultrasound Imaging of Gene Expression in Mammalian CellsSemantic proximity Read

Electroporation-Based Gene Delivery and Whole-Organoid Imaging in Human Retinal OrganoidsSemantic proximity Read

CRISPR-Cas9 Engineered Extracellular Vesicles for the Treatment of Dominant Progressive Hearing LossSemantic proximity Read

Multiplexed <sup>129</sup> Xe HyperCEST MRI detection of genetically-reconstituted bacterial protein nanoparticles in human cancer cellsSemantic proximity Read

Single cell transfection of human induced pluripotent stem cells using a droplet-based microfluidic systemSemantic proximity Read

Ultrasonic Reporter of Kinase ActivitySemantic proximity Read

A modular encapsulation system for precision delivery of proteins, nucleic acids and small moleculesSemantic proximity Read

Curvature-Encoded Photochemistry for Programmable Isolation and Fractionation of Extracellular and Plasma Membrane VesiclesSemantic proximity Read