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Evolutionary responses to acquiring a multidrug resistance plasmid are dominated by metabolic functions across diverse <i>Escherichia coli</i> lineages

2022-07-23

Abstract excerpt

Multidrug resistance (MDR) plasmids drive the spread of antibiotic resistance between bacterial lineages. The immediate impact of MDR plasmid acquisition on fitness and cellular processes varies among bacterial lineages, but how the evolutionary processes enabling the genomic integration of MDR plasmids vary is less well understood, particularly in clinical pathogens. Using diverse Escherichia coli lineages exper...

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Identifiers and source

Literature Corpus work
837fecbb-f4f0-5ba5-9c89-9aed6a00a7c7
DOI
10.1101/2022.07.22.501110
Open publication

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Evolutionary responses to acquiring a multidrug resistance plasmid are dominated by metabolic functions across diverse <i>Escherichia coli</i> lineagesDOI 10.1101/2022.07.22.501110
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