Diagnostic Accuracy and Yield of Determine Urine TB LF-LAM® for Detecting Tuberculosis Among Adults and Children with Advanced HIV Disease in Nigeria

Abstract excerpt

<h4>Introduction</h4> Tuberculosis (TB) diagnosis remains the weakest link in the care cascade, particularly among people living with HIV and AIDS (PLHIV) with advanced HIV disease (AHD), who are often cannot produce quality sputum for standard tests. Urine-based assays such as Determine Urine TB LF-LAM® offer a non-invasive, easy-to-collect alternative that can detect lipoarabinomannan antigen even in extrapulmo...

Topics

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• Antitubercular Agents
• Bronchoalveolar Lavage Fluid
• Molecular Diagnostic Techniques
• Monoclonal and Polyclonal Antibodies Research
• Mycobacterium research and diagnosis
• Mycobacterium tuberculosis
• Rifampin
• Tuberculosis Research and Epidemiology

Identifiers and source

Literature Corpus work

8363182c-0edb-5365-981a-b2dcf6f5c7d0

DOI

10.1101/2025.09.13.25335679