Article

The mechanism by which miR-499 feedback regulates the α- myosin heavy chain and β- myosin heavy chain gene axis in septic myocardial dysfunction

2024-01-31

Abstract excerpt

Cardiac failure due to sepsis is a common cause of death in patients with sepsis, but the specific mechanism leading to cardiac dysfunction is not clear. Therefore, we established a rat model of lipopolysaccharide (LPS)-induced sepsis-mediated cardiac dysfunction to investigate changes in the expression of miR-499 in the plasma and cardiac tissue and the potential mechanism. The results showed that after LPS stimu...

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Literature Corpus work: 82b5cfaa-160d-552b-a778-87bbf50d144d
DOI: 10.22541/au.170667850.02600528/v1

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