Article

NRP1 and furin as putative mediators of SARS-CoV-2 entry into human brain cells

2022-01-20

Abstract excerpt

<h4>ABSTRACT</h4> COVID-19 has prominent neurological manifestations including psychiatric symptoms, indicating significant synaptic pathology. Surprisingly, existing evidence suggests negligible expression of the key SARS-CoV-2 host cell entry mediators ACE2 and TMPRSS2 in human brain, which complicates understanding of the pathomechanisms of the neuropsychiatric manifestations in COVID-19. Recent studies sugg...

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Literature Corpus work: 82932626-d42c-5178-9eab-6434aa6d08c8
DOI: 10.1101/2022.01.19.476893

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