Article

Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping

2022-03-30

Abstract excerpt

<title>Abstract</title> <p>We present spatial-CITE-seq for high-plex protein and whole transcriptome co-mapping, which was firstly demonstrated for profiling 198 proteins and transcriptome in multiple mouse tissue types. It was then applied to human tissues to measure 283 proteins and transcriptome that revealed spatially distinct germinal center reaction in tonsil and early immune activation in skin at the COVID...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 81af44e0-3fc9-5ac5-b3fe-ada918f5ba33
DOI: 10.21203/rs.3.rs-1499315/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mappingDOI 10.21203/rs.3.rs-1499315/v1Read

Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mappingSemantic proximity Read

Spatial Proximity Sequencing Maps Developmental Dynamics in the Germinal CenterSemantic proximity Read

Dual spatially resolved transcriptomics for SARS-CoV-2 host-pathogen colocalization studies in humansSemantic proximity Read

Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplusSemantic proximity Read

Scalable spatial single-cell transcriptomics and translatomics in 3D thick tissue blocksSemantic proximity Read

Spatial dynamics of mammalian brain development and neuroinflammation by multimodal tri-omics mappingSemantic proximity Read

A framework for ultra-low input spatial tissue proteomicsSemantic proximity Read

Same-Slide Spatial Multi-Omics Integration Reveals Tumor Virus-Linked Spatial Reorganization of the Tumor MicroenvironmentSemantic proximity Read

Spatial transcriptome sequencing of FFPE tissues at cellular levelSemantic proximity Read

Spatial-ATAC-seq: spatially resolved chromatin accessibility profiling of tissues at genome scale and cellular levelSemantic proximity Read

Integration of Imaging-based and Sequencing-based Spatial Omics Mapping on the Same Tissue Section via DBiTplusSemantic proximity Read

Integrated protein and transcriptome high-throughput spatial profilingSemantic proximity Read