Back to search

Article

LDHA associated with Telomerase-related genes promotes tumorigenesis and progression of Lung adenocarcinoma

2025-07-02

Abstract excerpt

<title>Abstract</title> <p>Lung adenocarcinoma (LUAD) is a lung cancer subtype with poor prognosis and high heterogeneity, posing significant challenges in clinical management. Telomerase-related genes (TRGs), crucial for chromosomal stability and tumor progression, have an unclear link to LUAD prognosis. In this study, using genomic and clinical data from TCGA and GEO databases, we developed a 12-TRG-based risk...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
805145bc-77b9-5de6-9a7a-7ba23974cfe0
DOI
10.21203/rs.3.rs-6812165/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
LDHA associated with Telomerase-related genes promotes tumorigenesis and progression of Lung adenocarcinomaDOI 10.21203/rs.3.rs-6812165/v1
Identification of Lysosome-Related Features for Predicting Prognostic Tumor Microenvironment in Lung AdenocarcinomaSemantic proximity
A risk model including eight tumor microenvironment-related genes for prediction of lung cancer prognosisSemantic proximity
Systematical identifications of prognostic meaningful lung adenocarcinoma subtypes and the underlying mutational and expressional characters.Semantic proximity
Systematical identifications of prognostic meaningful lung adenocarcinoma subtypes and the underlying mutational and expressional charactersSemantic proximity
A 5-mRNA-Based Prognostic Signature of Survival in Lung AdenocarcinomaSemantic proximity
Genome‐scale analysis to identify prognostic markers and predict the survival of lung adenocarcinomaSemantic proximity
Transcriptomic investigation highlights tumor suppressive effects of TAGAP in lung adenocarcinomaSemantic proximity
Systematic Profiling of Invasion-related Genes Signature Predicts Prognostic Features and Identificates Molecular Subtypes of Lung AdenocarcinomaSemantic proximity
Subtype classification based on t cell proliferation-related regulator genes and risk model for predicting outcomes of lung adenocarcinomaSemantic proximity
Characterization of genomic instability-related genes predicts survival and therapeutic response in lung adenocarcinomaSemantic proximity
Development and Validation of Lactate Metabolism-Related lncRNA Signature as a Prognostic Model for Lung AdenocarcinomaSemantic proximity
Machine learning-based prognostic model of lactylation-related genes for predicting prognosis and immune infiltration in patients with lung adenocarcinomaSemantic proximity
Select a neighboring publication to make it the new centre.