Article

Distinct T Cell Functional Profiles in Sars-Cov-2 Seropositive and Seronegative Children Associated with Endemic Human Coronavirus Cross-Reactivity

2023-07-20

Abstract excerpt

SARS-CoV-2 infection in children typically results in asymptomatic or mild disease. There is a paucity of studies on SARS-CoV-2 antiviral immunity in African children. We investigated SARS-CoV-2-specific T cell responses in 71 unvaccinated asymptomatic South African children who were seropositive or seronegative for SARS-CoV-2. SARS-CoV-2-specific CD4+ T cell responses were detectable in 83% of seropositive and 60...

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Literature Corpus work: 7fec0bf7-cfcc-5be7-8e52-1bbd4f9efc98
DOI: 10.2139/ssrn.4510529

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