Article

METTL13 Inhibits Progression of Clear Cell Renal Cell Carcinoma with Repression on PI3K/AKT/mTOR/HIF-1α Pathway and c-Myc Expression

2021-02-19

Abstract excerpt

<title>Abstract</title> <p>Background: Clear cell renal cell carcinoma (ccRCC) is the most common and aggressive type of renal malignancy. Methyltransferase like 13 (METTL13) functions as an oncogene in most of human cancers, but its function and mechanism in ccRCC remain unreported. <h4>Methods:</h4> qRT-PCR, western blot and immunohistochemistry were used to detect METTL13’s expressions in tissues. The effects...

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Literature Corpus work: 7fa4609a-cf47-503f-ab83-f7ae01abb906
DOI: 10.21203/rs.3.rs-214061/v1

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