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Manual Pressure Techniques Activate Descending Pain-Modulatory Pathways and Reduce Headache Intensity in Chronic Tension-Type Headache: A Randomized Crossover Trial

2026-03-28

Abstract excerpt

<title>Abstract</title> <p>Introduction: Chronic tension-type headache (CTTH) is characterized by central sensitization and impaired descending pain modulation. Manual pressure techniques are hypothesized to engage descending pain-modulatory pathways, a mechanism quantifiable through conditioned pain modulation protocols. We investigated whether manual pressure techniques activate these pathways and compared the...

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Literature Corpus work
7edd6da4-5c80-5ede-8819-0b84b141593b
DOI
10.21203/rs.3.rs-9222006/v1
Open publication

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Manual Pressure Techniques Activate Descending Pain-Modulatory Pathways and Reduce Headache Intensity in Chronic Tension-Type Headache: A Randomized Crossover TrialDOI 10.21203/rs.3.rs-9222006/v1
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