Article

Kaposi’s sarcoma-associated herpesvirus fine-tunes the temporal expression of late genes by manipulating a host RNA quality control pathway

2020-02-20

Abstract excerpt

Kaposi’s sarcoma-associated herpesvirus (KSHV) is a human oncogenic nuclear DNA virus that expresses its genes using the host cell transcription and RNA processing machinery. As a result, KSHV transcripts are subject to degradation by at least two host-mediated nuclear RNA decay pathways, PABPN1 and PAPα/γ-mediated RNA decay (PPD) and an ARS2-dependent decay pathway. Here, we present global analyses of viral trans...

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Literature Corpus work: 7eb1317b-4f69-5780-9a1d-32de745358b2
DOI: 10.1101/2020.02.18.955526

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