Article

Theoretical framework and experimental validation of multiplexed analyte quantification using cross-reactive affinity reagents

2023-11-25

Abstract excerpt

Gold standard immunoassays depend on specific affinity reagents for accurate molecular quantification. Any cross-reactivity of affinity reagents, wherein the reagent non-specifically binds to unintended molecules, can create false positive binding signals and result in inaccurate quantification of analytes. Mitigating cross-reactivity represents one of the greatest challenges in molecular diagnostics, and remains...

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Literature Corpus work: 7e216d40-2aee-55bc-9b8c-9ff8024ef806
DOI: 10.1101/2023.11.24.568623

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