Article

Long read metagenomics-based precise tracking of bacterial strains and genomic changes after fecal microbiota transplantation

2024-09-30

Abstract excerpt

Fecal microbiota transplantation (FMT) has revolutionized the treatment of recurrent Clostridioides difficile infection (rCDI) and is being evaluated across other diseases. Accurate tracking of bacterial strains that stably engraft in recipients is critical for understanding the determinants of strain engraftment, evaluating their correlation with clinical outcomes, and guiding the development of therapeutic bacte...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7d0ff969-2f63-5e3d-89e7-5531e062d59a
DOI: 10.1101/2024.09.30.615906

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Long read metagenomics-based precise tracking of bacterial strains and genomic changes after fecal microbiota transplantationDOI 10.1101/2024.09.30.615906Read

Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomesSemantic proximity Read

Metagenomic strain detection with SameStr: identification of a persisting core gut microbiota transferable by fecal transplantationSemantic proximity Read

Variability of strain engraftment and predictability of microbiome composition after fecal microbiota transplantation across different diseasesSemantic proximity Read

Tracking microbial colonization in fecal microbiota transplantation experiments via genome-resolved metagenomicsSemantic proximity Read

Microbial Strain Engraftment, Persistence and Replacement after Fecal Microbiota TransplantationSemantic proximity Read

Identification of clinical and ecological determinants of strain engraftment after fecal microbiota transplantation using metagenomicsSemantic proximity Read

Intraspecies strain exclusion, antibiotic pretreatment, and donor selection control microbiota engraftment after fecal transplantationSemantic proximity Read

Species- and strain-level assessment using <i>rrn</i> long-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjectsSemantic proximity Read

Strain-Level Genetic Heterogeneity and Colonization Dynamics Drive Microbiome Therapeutic EfficacySemantic proximity Read

Species- and strain-level assessment using rrn long-amplicons suggests donor’s influence on gut microbial transference via fecal transplants in metabolic syndrome subjectsSemantic proximity Read

Fecal microbiota transplantation brings about bacterial strain displacement in patients with inflammatory bowel diseasesSemantic proximity Read

Strain-resolved microbiome sequencing reveals mobile elements that drive bacterial competition on a clinical timescaleSemantic proximity Read