Article

Evolutionary origins of multidrug and drug‐specific efflux pumps in bacteria

1998-03-01

Abstract excerpt

The available genomic sequences of three pathogenic and three nonpathogenic bacteria were analyzed to identify known and putative drug‐specific and multidrug resistance transport systems. Escherichia coli was found to encode 29 such pumps, and with the exception of the archaebacterium Meth anococcus jannaschii, the numbers of multidrug efflux pumps encoded within genomes of the other organisms were found to be app...

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Literature Corpus work: 7c70a8b8-e73f-571e-971b-8d4780616818
DOI: 10.1096/fasebj.12.03.265

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