Article

A concurrent canonical and modified miRNAome pan-cancer study on TCGA and TARGET cohorts leads to an enhanced resolution in cancer

2021-05-20

Abstract excerpt

<h4>ABSTRACT</h4> MiRNA Epitranscriptomics has placed a new layer of complexity in the cancer field. Despite the fast-growing interest in miRNA editing and shifted miRNA isoforms, a simultaneous study of both modifications in cancer is still missing. Here, we concurrently profiled multiple miRNA modifications, including A-to-I RNA editing and shifted miRNA isoforms, in >13K adult and pediatric tumor samples acros...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7c1c42e8-aa01-55f0-b128-bf50d72a1270
DOI: 10.1101/2021.05.18.444694

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A concurrent canonical and modified miRNAome pan-cancer study on TCGA and TARGET cohorts leads to an enhanced resolution in cancerDOI 10.1101/2021.05.18.444694Read

Tumor IsomiR Encyclopedia (TIE): a pan-cancer database of miRNA isoformsSemantic proximity Read

OncomiR: an online resource for exploring pan-cancer microRNA dysregulationSemantic proximity Read

RNA Editing Dynamically Rewrites the Cancer Code.Semantic proximity Read

OMCD: OncoMir Cancer DatabaseSemantic proximity Read

OMCD: OncomiR Cancer DatabaseSemantic proximity Read

MicroRNAome genome: a treasure for cancer diagnosis and therapy.Semantic proximity Read

Disparities in Lung Cancer: miRNA Isoform Characterization in Lung AdenocarcinomaSemantic proximity Read

Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors.Semantic proximity Read

The Integrative Studies on the Functional A-to-I RNA Editing Events in Human CancersSemantic proximity Read

Classification of heterogeneous genetic variations of microRNA regulome in cancer.Semantic proximity Read

The role of miRNAs in cancer: from pathogenesis to therapeutic implications.Semantic proximity Read

Pan-Cancer analysis of somatic mutations in miRNA genesSemantic proximity Read