Article

Probabilistic quotient’s work & pharmacokinetics’ contribution: countering size effect in metabolic time series measurements

2022-01-20

Abstract excerpt

Metabolomic time course analyses of biofluids are highly relevant for clinical diagnostics. However, many sampling methods suffer from unknown sample sizes commonly known as size effects. This prevents absolute quantification of biomarkers. Recently, several mathematical post acquisition normalization methods have been developed to overcome these problems either by exploiting already known pharmacokinetic informat...

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Literature Corpus work: 7be151f4-affb-5a6b-b172-f12f5e7ca98d
DOI: 10.1101/2022.01.17.476591

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