Article

Exploring the immune characteristics of HPV-positive HNSCC patients based on bioinformatics research and identifying SERPINE1 as a key factor affecting the prognosis of HNSCC patients with HPV

2024-11-21

Abstract excerpt

<title>Abstract</title> <p>Background Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with an increasing trend of its incidence. Human papillomavirus (HPV) positive HNSCC patients generally have a favorable survival and a promising responsiveness to radiotherapy, chemoradiotherapy and checkpoint blockades. However, the immunological characteristics of HPV-positive patients...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7bbf6173-afef-54a0-8646-4f2537af4f1a
DOI: 10.21203/rs.3.rs-5346655/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Exploring the immune characteristics of HPV-positive HNSCC patients based on bioinformatics research and identifying SERPINE1 as a key factor affecting the prognosis of HNSCC patients with HPVDOI 10.21203/rs.3.rs-5346655/v1Read

Increased RBPs associated with HPV play a role in reducing the survival of patients with head and neck cancerSemantic proximity Read

Identification of SERPINE1, PLAU and ACTA1 as biomarkers of head and neck squamous cell carcinoma based on integrated bioinformatics analysisSemantic proximity Read

Identification of Four Key Prognostic Genes and Three Potential Drugs in Human Papillomavirus Negative Head and Neck Squamous Cell CarcinomaSemantic proximity Read

Identification of AREG, STAG3, C19orf57 and CAV1 as key prognostic factors in HPV- negative head and neck squamous cell carcinomaSemantic proximity Read

Prognostic Significance and Therapeutic Potential of SERPINE1 in Head and Neck Squamous Cell CarcinomaSemantic proximity Read

Identification of key survival genes of the tumor microenvironment and immune infiltration in head and neck squamous cell carcinomaSemantic proximity Read

Molecular mechanisms of human papillomavirus-related carcinogenesis in head and neck cancerSemantic proximity Read

Comprehensive Analysis of Immune Cell Enrichment In The Tumor Microenvironment of Head And Neck Squamous Cell CarcinomaSemantic proximity Read

Bioinformatics molecular analysis of prognostic-related genes and drug sensitivity and resistance in head and neck squamous cell carcinomasSemantic proximity Read

In silico analysis of driver genes in squamous cell carcinoma of the cervix: insights into their biological functions, prognosis, immune infiltration, and therapy.Semantic proximity Read

A key genomic signature associated with lymphovascular invasion in head and neck squamous cell carcinomaSemantic proximity Read