Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

In silico analysis of driver genes in squamous cell carcinoma of the cervix: insights into their biological functions, prognosis, immune infiltration, and therapy.

World journal of surgical oncology - 1 Jun 2026

Bhat Samatha, Devi Vasudha, Kabekkodu Shama Prasada

Abstract excerpt

BACKGROUND: Cervical cancer is the fourth most common cancer affecting the female reproductive system worldwide. Although several studies have reported recurrent mutations in cervical squamous cell carcinoma (SCC), a comprehensive understanding of the clinically relevant driver genes remains limited. Unlike previous single-cohort or frequency-based reports, this study integrates four independent cervical squamous...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Carcinoma, Squamous Cell

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Gene Regulatory Networks

Share to Mutation

Share to Prognosis

Share to Protein Interaction Maps

Share to Uterine Cervical Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42226181
DOI: 10.1186/s12957-026-04435-y
PMCID: PMC13435706

Genes

EP300
NOTCH1
PIK3CA
STK11
TP53
ARID1A
CASP8
ERBB2
FAT1
KMT2C
KMT2D
KRAS
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

In silico analysis of driver genes in squamous cell carcinoma of the cervix: insights into their biological functions, prognosis, immune infiltration, and therapy.PMID 42226181Read ↗

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significanceSemantic proximity Read ↗

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.Semantic proximity Read ↗

Screening and Identification of Novel Biomarkers Associated with Cutaneous Squamous Cell CarcinomaSemantic proximity Read ↗

Identification of hub genes as potential diagnostic biomarkers for cervical cancer: A bioinformatic approachSemantic proximity Read ↗

The differences in immune features and genomic profiling between squamous cell carcinoma and adenocarcinoma - A multi-center study in Chinese patients with uterine cervical cancer.Semantic proximity Read ↗

Transcriptomes of cervical cancer provide novel insights into dysregulated pathways, potential therapeutic targets, and repurposed drugsSemantic proximity Read ↗

Six Novel Biomarkers for Diagnosis and Prognosis of Esophageal squamous cell carcinoma: validated by scRNA-seq and qPCRSemantic proximity Read ↗

Screening and Identification of Potential Biomarkers Associated with Cutaneous Squamous Cell CarcinomaSemantic proximity Read ↗

Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significanceSemantic proximity Read ↗

Comparative Analysis of Mutation Status and Immune Landscape for Squamous Cell Carcinomas at Different Anatomical sites.Semantic proximity Read ↗

The relevance between the immune response-related gene module and clinical traits in head and neck squamous cell carcinomaSemantic proximity Read ↗

Identification of Potential Driver Genes Based on Multi-Genomic Data in Cervical CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.