Article

Proteomics and genomics: A hypothesis-free approach to the study of the role of visceral adiposity in the pathogenesis of the polycystic ovary syndrome.

2008-03-01

Abstract excerpt

The polycystic ovary syndrome (PCOS) is possibly the most common endocrine disorder in premenopausal women. The primary defect in PCOS consists of an exaggerated androgen secretion by the ovaries and the adrenal glands of affected women, which is amplified by several mechanisms including abdominal adiposity and insulin resistance. Abdominal adiposity contributes to hyperandrogenism by favoring insulin resistance a...

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Literature Corpus work: 7b88c0c4-7953-5ccb-96f2-376a0b2f7e30
DOI: 10.1002/prca.200780031

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