Article

Establishment of prediction models for lung cancer NOG/PDX models: A guideline for machine learning in small biomedical datasets

2020-09-16

Abstract excerpt

<h4>Background: </h4> Targeted therapy and immune checkpoint inhibitors are the most promising treatments for lung cancers but still facing multiple challenges, including resistance and individual difference. Therefore, patient-derived tumor xenografts (PDX) models are developed for drug discovery and screening. NOG mice is under the destruction of the interleukin-2 (IL-2) receptor common gamma chain, which is app...

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Literature Corpus work: 7b74c4af-a828-5908-860c-e9fb9fcd6a48
DOI: 10.21203/rs.3.rs-73446/v1

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