Article
Identification and validation of a genomic mutation signature as a predictor for immunotherapy in NSCLC.
Bioscience reports - 30 Nov 2022
Wang Zemin, Ge You, Li Han, Fei Gaoqiang, Wang Shuai, Wei Pingmin
Abstract excerpt
Currently, the benefits of immune checkpoint inhibitor (ICI) therapy prediction via emerging biomarkers have been identified, and the association between genomic mutation signatures (GMS) and immunotherapy benefits has been widely recognized as well. However, the evidence about non-small cell lung cancer (NSCLC) remains limited. We analyzed 310 immunotherapy patients with NSCLC from the Memorial Sloan Kettering...
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