Article

A metagene of NRF2 expression is a prognostic biomarker in all stage colorectal cancer

2019-07-02

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objective</h4> Nrf2 overexpression confers poor prognosis in some cancers but its role in colorectal cancer (CRC) is unknown. Due to its role as a transcription factor we hypothesise a metagene of NRF2 regulated genes could act as a prognostic biomarker in CRC. <h4>Design</h4> Using known NRF2 regulated genes, we defined an NRF2 metagene to represent the pathway expression using principal...

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Literature Corpus work: 7b264275-1259-59ad-93d2-9658a69d5587
DOI: 10.1101/690974

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