Article

Identification of a nonsense mutation in TNNI3K associated with cardiac conduction disease and dilated cardiomyopathy

2019-12-09

Abstract excerpt

<title>Abstract</title> <p>Background Cardiac conduction disease(CCD) and dilated cardiomyopathy(DCM) are two common cardiovascular diseases which can lead to life-threatening conditions. The importance of heredity in these two diseases has been realized in recent years. Several casual genes have been found to be implicated in CCD and DCM such as LMNA,SCN5A,TTN,TNNI3K and so on. Rare genetic mutations in TNNI3K h...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 7a89b1fb-5f4b-5ff9-bdbf-e21bed2c5b2f
DOI: 10.21203/rs.2.18398/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Identification of a nonsense mutation in TNNI3K associated with cardiac conduction disease and dilated cardiomyopathyDOI 10.21203/rs.2.18398/v1Read

Whole exome sequencing identifies a novel mutation (c.333 + 2T > C) of TNNI3K in a Chinese family with dilated cardiomyopathy and cardiac conduction disease.Semantic proximity Read

[Identification of variants in TNNI3 gene in two children with restrictive cardiomyopathy].Semantic proximity Read

Targeted next-generation sequencing of candidate genes reveals novel mutations in patients with dilated cardiomyopathy.Semantic proximity Read

[Mutation screening for the causative gene in a four-generation Chinese pedigree with progressive cardiac conduction defect].Semantic proximity Read

Next-Generation Sequencing Screening Reveals Novel Genetic Variants for Dilated Cardiomyopathy in Pediatric Chinese PatientsSemantic proximity Read

A novel arginine to tryptophan (R144W) mutation in troponin T (cTnT) gene in an indian multigenerational family with dilated cardiomyopathy (FDCM).Semantic proximity Read

Genetic variants in Chinese patients with sporadic dilated cardiomyopathy: a cross-sectional studySemantic proximity Read

The cardiac sodium channel mutation delQKP 1507-1509 is associated with the expanding phenotypic spectrum of LQT3, conduction disorder, dilated cardiomyopathy, and high incidence of youth sudden death.Semantic proximity Read

TNNT2 Gene Polymorphisms are Associated with Susceptibility to Idiopathic Dilated Cardiomyopathy in Kazak and Han Chinese.Semantic proximity Read

Deletion in TNNI3 gene is associated with restrictive cardiomyopathy.Semantic proximity Read

Whole exome sequencing identifies novel candidate mutations in a Chinese family with left ventricular noncompaction.Semantic proximity Read

Restrictive Cardiomyopathy Resulting from a Troponin I Type 3 Mutation in a Chinese Family.Semantic proximity Read