Article

Binucleated cell formation and oncogene expression after particulate matter exposure is preceded by microtubule disruption, dysregulated cell cycle, prolonged mitosis, and septin binding

2024-01-08

Abstract excerpt

Several biopersistent high aspect ratio nanomaterials show pronounced pathogenic effects, from chronic lung inflammation and fibrosis to cancer. For example, asbestos fibers are classified as carcinogens, whereas the carcinogenicity of highly inflammatory multi-wall carbon nanotubes (MWCNTs), and TiO 2 nanomaterials is still being evaluated. The exact early mechanisms of their pathogenicity towards inflammation a...

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Literature Corpus work: 7a0ad6d8-4d8b-5c6d-a224-f297aff11330
DOI: 10.1101/2024.01.07.574515

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Binucleated cell formation and oncogene expression after particulate matter exposure is preceded by microtubule disruption, dysregulated cell cycle, prolonged mitosis, and septin bindingDOI 10.1101/2024.01.07.574515Read

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