Article
From blood to pluripotency: Fibrocytes as a reprogrammable somatic cell source for bovine iPSCs
2025-10-31
Abstract excerpt
Fibrocytes represent a distinct somatic cell type derived from peripheral blood leukocytes, first described as spindle-shaped adherent cells with dual hematopoietic and mesenchymal features. Although fibrocytes were identified in early descriptive studies across several mammalian systems, most of this work predated modern molecular approaches, and the cells remain incompletely defined at the molecular level and ha...
Topics
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- Cancer Cells and Metastasis
- Cancer-related molecular mechanisms research
- Dupuytren's Contracture and Treatments
- Erythrocyte Function and Pathophysiology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mesenchymal stem cell research
- MicroRNA in disease regulation
- Single-cell and spatial transcriptomics
Identifiers and source
- Literature Corpus work
- 79687c96-da76-59c4-bb1f-4fd0434424b1
- DOI
- 10.1101/2025.10.30.685680
